Isoflurophate

Isoflurophate

SCHEMBL63841

CC(C)OP(=O)(F)OC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Isoflurophate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 1.00
CTSA P10619 1/20 1.00
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoflurophate SCHEMBL8995748 0.91 CTSA (0.83) CTSAACHEALDH1A1L3MBTL1KDM4E
Isoflurophate SCHEMBL28660597 0.87 CTSA (0.75) CTSAACHEALDH1A1L3MBTL1KDM4E
SCHEMBL510277 0.85
Isoflurophate SCHEMBL1525589 0.83 CTSA (0.68) CTSAACHEKDM4ETDP1
SCHEMBL3133686 0.80
SCHEMBL7537376 0.80 CTSA (0.67) CTSAACHEALDH1A1L3MBTL1KDM4E
SCHEMBL15137787 0.79 CTSA (0.64) CTSAACHEALDH1A1KDM4EPOLB
Isopropyl Methylphosphonofluoridate SCHEMBL13442719 0.78
Isopropyl Methylphosphonofluoridate SCHEMBL50256 0.78
Isopropyl Methylphosphonofluoridate SCHEMBL3917642 0.78 CTSA (0.63) CTSAACHEALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13831 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304919-B Organic fluorescent sensing array for selectively distinguishing and detecting sarin and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2026-05-26 CN claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 US claimed
US-20250343325-A1 COMPOSITE SEPARATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2025-11-06 US claimed
EP-4632934-A1 COMPOSITE SEPARATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Contemporary Amperex Technology Co., Limited (CN) 2025-10-15 EP claimed
EP-4631514-A1 ORAL POLYPEPTIDE COMPOSITION AND USE THEREOF Hefei Tianhui Biotech Co., Ltd. (CN) 2025-10-15 EP claimed
US-20250281579-A1 Methods and Compositions for Oral Administration of Proteins ORAMED PHARMACEUTICALS INC (IL) 2025-09-11 US claimed
US-12398445-B2 Background Rn-rejected actinide in air spectroscopy PURDUE RESEARCH FOUNDATION (US) 2025-08-26 US claimed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 EP claimed
US-4458013-A DIAGNOSIS OF PANCREATIC DISEASES DAINABOT KABUSHIKI KAISHA (JP) 1984-07-03 US claimed
US-4439427-A Method and composition for treating pediculosis SOFT SHEEN PRODUCTS, INC. (US) 1984-03-27 US claimed
US-4431582-A WOUND HEALING AGENTS RESEARCH CORPORATION (US) 1984-02-14 US claimed
US-4426448-A PREPARARATION OF CAFFEIC ACID KIKKOMAN CORPORATION (JP) 1984-01-17 US claimed
EP-0078451-A1 Reagents for determining the ristocetin cofactor (von Willebrand's factor) BEHRINGWERKE Aktiengesellschaft (DE) 1983-05-11 EP claimed
US-4370416-A CULTIVATION OF ASPERGILLUS OR BOTRYTIS KIKKOMAN CORPORATION (JP) 1983-01-25 US claimed
US-4364926-A INHIBITORS OF TRANSFERASES; ALKALI RESISTANCE; HEAT RESISTANCE; DENTIFRICES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1982-12-21 US claimed
US-4245051-A ANTICOAGULANT ROCKEFELLER UNIVERSITY (US) 1981-01-13 US claimed
US-4108950-A Process for preparing organophosphorus and organophosphono fluorines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1978-08-22 US claimed
US-3986930-A COLORIMETRY, S-ACYL COMPOUNDS DAINIPPON PHARMACEUTICAL CO., LTD. (JA) 1976-10-19 US claimed