Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoflurophate SCHEMBL63841 | 0.80 | CTSA (1.00) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3133686 | 0.73 | — | — | |
| Isoflurophate SCHEMBL8995748 | 0.73 | CTSA (0.83) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| SCHEMBL510277 | 0.73 | — | — | |
| SCHEMBL80155 | 0.72 | CTSA (0.56) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| Isopropyl Methylphosphonofluoridate SCHEMBL50256 | 0.71 | — | — | |
| Isopropyl Methylphosphonofluoridate SCHEMBL13442719 | 0.71 | — | — | |
| Isopropyl Methylphosphonofluoridate SCHEMBL3917642 | 0.71 | CTSA (0.63) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| SCHEMBL25174107 | 0.69 | CTSA (0.53) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| Methylphosphonic Acid Diisopropyl Ester SCHEMBL472052 | 0.69 | CTSA (0.53) | CTSAACHEALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202998-A1 | SYNTHESIS OF STABLE QUINONE AND PHOTOREACTIVE KETONE PHOSPHORAMIDITE REAGENTS FOR SOLID PHASE SYNTHESIS OF PHOTOREACTIVE-OLIGOMER CONJUGATES | Exiqon A/S (DK) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001004129-A1 | SYNTHESIS OF STABLE QUINONE AND PHOTOREACTIVE KETONE PHOSPHORAMIDITE REAGENTS FOR SOLID PHASE SYNTHESIS OF PHOTOREACTIVE-OLIGOMER CONJUGATES | EXIQON A/S (DK) | 2001-01-18 | — | — | WO | disclosed |
| US-5750735-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5744465-A | Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0504612-B1 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5623081-A | USING BENZYLOXYACETALDEHYDE DIMETHYL ETHER, HALOGENATED 1-PHENYLMETHOXY-4-PENTEN-2-OL; CYCLIZATION | LIN YANG-I (US) | 1997-04-22 | — | — | US | disclosed |
| US-5602118-A | A 2-((2-SUBSTITUTED ALKYL)FUR-3-YL)-THIO-),3-CARBOXY-2-CARBOPENEM DERIVATIVES; EFFECTIVE AGAINST BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA | AMERICAN CYANAMID COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| US-5371215-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5189158-A | 4-SUBSTITUTED AZETIDINONES AS PRECURSORS TO 2-SUBSTITUTED-3-CARBOXY CARBAPENEM ANTIBIOTICS AND A METHOD OF PRODUCING THEM | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0504612-A2 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |