Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 13/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383964 | 0.87 | MAP3K8 (0.47) | EGFRERBB2IDO1MAP3K8 | |
| SCHEMBL6379765 | 0.87 | EGFR (0.57) | EGFRERBB2GAKMAP3K8 | |
| SCHEMBL5888336 | 0.86 | MAP2K1 (0.52) | EGFRERBB2GAK | |
| SCHEMBL6381724 | 0.86 | EGFR (0.47) | EGFRERBB2GAKTDO2 | |
| SCHEMBL6382153 | 0.86 | EGFR (0.50) | EGFRERBB2GAKIDO1 | |
| SCHEMBL6384067 | 0.86 | EGFR (0.58) | EGFRERBB2PRKCQGAKIDO1 | |
| SCHEMBL6383946 | 0.86 | EGFR (0.61) | EGFRERBB2GAK | |
| SCHEMBL6381773 | 0.85 | EGFR (0.60) | EGFRERBB2IDO1TDO2 | |
| SCHEMBL6383708 | 0.84 | EGFR (0.59) | EGFRERBB2MAP3K8 | |
| SCHEMBL6384653 | 0.84 | MAP3K8 (0.49) | EGFRERBB2MAP3K8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |