Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273344 | 0.83 | NPC1 (0.50) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL28365111 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL28369622 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL2032921 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL28365113 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL30445144 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL20394045 | 0.81 | CYP1A2 (0.52) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL17093338 | 0.81 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2ALPIPKM | |
| SCHEMBL28216354 | 0.80 | TAAR1 (0.50) | NPC1RAB9ACYP1A2TRPA1SLC6A2 | |
| SCHEMBL27644703 | 0.80 | NPC1 (0.47) | NPC1RAB9ACYP1A2ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658802-A1 | PROCESS FOR MAKING DRIMANE ALDEHYDES | Firmenich SA (CH) | 2025-12-10 | — | — | EP | disclosed |
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | AGAIN BIO APS (DK) | 2025-11-27 | — | — | US | disclosed |
| US-12312627-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| EP-4414451-A2 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4 HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | Genomatica, Inc. (US) | 2024-08-14 | — | — | EP | disclosed |
| WO-2024160757-A1 | PROCESS FOR MAKING DRIMANE ALDEHYDES | FIRMENICH SA (CH) | 2024-08-08 | — | — | WO | disclosed |
| EP-2989113-B1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | GENOMATICA INC (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11753222-B2 | Powdered pouch and method of making same | MONOSOL, LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20230159979-A1 | TRANSDUCERS, NANOPARTICLE TRANSDUCER DEVICES AND SYSTEMS, AND RELATED METHODS OF USE | UNIVERSITY OF WASHINGTON (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230134936-A1 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | GENOMATICA INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-7947483-B2 | Methods and organisms for the growth-coupled production of 1,4-butanediol | GENOMATICA, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7858350-B2 | Microorganisms for the production of 1,4-butanediol | GENOMATICA, INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100112654-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2010-05-06 | — | — | US | disclosed |
| US-20100011456-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | VERENIUM CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |
| EP-2137315-A2 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | Genomatica, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| US-20090075351-A1 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | AGAIN BIO APS (DK) | 2009-03-19 | — | — | US | disclosed |
| US-20090047719-A1 | Methods and organisms for the growth-coupled production of 1,4-butanediol | AGAIN BIO APS (DK) | 2009-02-19 | — | — | US | disclosed |
| WO-2008115840-A2 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | GENOMATICA, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| EP-1373889-A2 | BIOSENSORS, REAGENTS AND DIAGNOSTIC APPLICATIONS OF DIRECTED EVOLUTION | Maxygen, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002010750-A2 | BIOSENSORS, REAGENTS AND DIAGNOSTIC APPLICATIONS OF DIRECTED EVOLUTION | MAXYGEN, INC. (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | HSD17B10, HSD17B12, HADHB | NPC1 3614/4885RAB9A 4729/4885CYP1A2 411/4885 |
| US-20100011456-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | POLN, POLM, POLI | NPC1 2937/4885RAB9A 4697/4885CYP1A2 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.