Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 1.00 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810099 | 0.90 | — | — | |
| SCHEMBL7758009 | 0.84 | CES2 (0.72) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL28546145 | 0.83 | CES2 (0.70) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL9770778 | 0.83 | CES2 (0.70) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL28140535 | 0.80 | CES2 (0.67) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL810202 | 0.79 | — | — | |
| SCHEMBL23950441 | 0.78 | CES2 (0.64) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL23950131 | 0.78 | CES2 (0.64) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL14477972 | 0.78 | CES2 (0.64) | CES2CES1PPARGPPARDPPARA | |
| SCHEMBL23950237 | 0.78 | CES2 (0.64) | CES2CES1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225162-B1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PROD & CHEM (US) | 2005-03-16 | — | — | EP | claimed |
| EP-0193187-B1 | PROCESS FOR PREPARING CRYSTALLINE AROMATIC POLYETHERKETONES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-06-13 | — | — | EP | claimed |
| CN-114605237-B | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-114605237-A | Preparation method and application of fluoroalkyl ketone compound | 武汉大学 | 2022-06-10 | — | — | CN | disclosed |
| WO-2014165861-A1 | METAL-CATALYZED COUPLING OF ARYL AND VINYL HALIDES WITH ALPHA, ALPHA-DIFLUOROCARBONYL COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-10-09 | — | — | WO | disclosed |
| EP-0787143-A2 | PHENYL PEPTIDES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID PEPTIDES | LABORATOIRE LAPHAL (FR) | 1997-08-06 | — | — | EP | disclosed |
| WO-1997001576-A2 | PHENYL PEPTIDES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID PEPTIDES | LABORATOIRE LAPHAL (FR) | 1997-01-16 | — | — | WO | disclosed |