Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.51 |
| ▸ | BCL2 | P10415 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587757 | 0.93 | MCL1 (0.54) | MCL1BCL2HTR6ROCK1BAD | |
| SCHEMBL6384954 | 0.88 | MCL1 (0.50) | MCL1BCL2HTR6ROCK1BAD | |
| SCHEMBL7958584 | 0.85 | HTR6 (0.50) | MCL1BCL2HTR6ROCK1BAD | |
| SCHEMBL4328875 | 0.82 | HTR6 (0.52) | MCL1BCL2HTR6ROCK1SRD5A2 | |
| SCHEMBL18049242 | 0.81 | HTR6 (0.67) | MCL1BCL2HTR6ROCK1 | |
| SCHEMBL20337898 | 0.80 | HTR6 (0.48) | MCL1BCL2HTR6ROCK1 | |
| SCHEMBL4323501 | 0.80 | HTR6 (0.52) | MCL1BCL2HTR6ROCK1 | |
| SCHEMBL23956093 | 0.80 | HTR2C (0.56) | MCL1BCL2HTR6ROCK1 | |
| SCHEMBL7958950 | 0.80 | KLKB1 (0.49) | MCL1BCL2HTR6ROCK1BAD | |
| Fumaric Acid SCHEMBL29435347 | 0.79 | HTR2C (0.50) | MCL1BCL2HTR6PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577305-A1 | Oral antidiabetic agents | WARNER-LAMBERT COMPANY LLC (US) | 2005-09-21 | — | — | EP | disclosed |
| CN-1558897-A | oral antidiabetic agent | ����-�����ع�˾ | 2004-12-29 | — | — | CN | disclosed |
| US-20030171377-A1 | Antidiabetic agents | BIGGE CHRISTOPHER FRANKLIN (US) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171377-A1 | Antidiabetic agents | SLC5A1, SLC5A2, GLP1R | MCL1 3940/4885BCL2 3512/4885HTR6 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.