Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 13/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 13/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384509 | 1.00 | ADORA3 (1.00) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4389767 | 0.90 | ADORA3 (0.81) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8820620 | 0.88 | ADORA3 (0.79) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8820609 | 0.88 | ADORA3 (0.79) | ADORA3ADORA2AADORA1 | |
| SCHEMBL14424395 | 0.88 | ADORA1 (0.79) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8818548 | 0.88 | ADORA3 (0.85) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8817565 | 0.88 | ADORA3 (0.78) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8818565 | 0.88 | ADORA3 (0.85) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8819510 | 0.88 | ADORA3 (0.78) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8819497 | 0.88 | ADORA3 (0.78) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537135-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022573-A2 | ADENOSINE A3 RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2004-03-18 | — | — | WO | disclosed |