Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 7/20 | 0.47 |
| ▸ | CDC25B | P30305 | 7/20 | 0.47 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 3/20 | 0.45 |
| ▸ | RORA | P35398 | 2/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | OSBP | P22059 | 1/20 | 0.43 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782768 | 0.78 | NPC1L1 (0.60) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL16152196 | 0.76 | PLA2G1B (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL30653161 | 0.76 | PLA2G1B (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL8408231 | 0.76 | PLA2G1B (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL18541413 | 0.72 | INPP5D (0.73) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL6560622 | 0.72 | INPP5D (0.62) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL6560618 | 0.72 | INPP5D (0.62) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL7127648 | 0.71 | INPP5D (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL7127645 | 0.71 | INPP5D (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL20111156 | 0.71 | PLA2G1B (0.49) | PLA2G1BNPC1L1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004382-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2005-01-06 | — | — | US | disclosed |
| US-6759400-B2 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2004-07-06 | — | — | US | disclosed |
| EP-0946584-B1 | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2003-04-23 | — | — | EP | disclosed |
| US-20030032824-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2003-02-13 | — | — | US | disclosed |
| EP-0946584-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028323-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032824-A1 | Meiosis regulating compounds | MNS1, NR5A1, NASP | PLA2G1B 4092/4885NPC1L1 2280/4885MEN1 231/4885 |
| US-20050004382-A1 | Meiosis regulating compounds | NASP, MNS1, NR5A1 | PLA2G1B 4307/4885NPC1L1 2324/4885MEN1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.