Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 7/20 | 0.44 |
| ▸ | CDC25B | P30305 | 7/20 | 0.44 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | RORA | P35398 | 2/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | OSBP | P22059 | 1/20 | 0.40 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408231 | 1.00 | PLA2G1B (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL30653161 | 1.00 | PLA2G1B (0.55) | PLA2G1BNPC1L1MEN1KMT2AUSP2 | |
| SCHEMBL16152194 | 0.81 | USP2 (0.42) | PLA2G1BUSP2CDC25ACDC25BINPP5D | |
| SCHEMBL8408230 | 0.81 | USP2 (0.42) | PLA2G1BUSP2CDC25ACDC25BINPP5D | |
| Ergosterol Peroxide SCHEMBL14067806 | 0.79 | PLA2G1B (0.46) | PLA2G1BMEN1KMT2AUSP2LMNA | |
| Ergosterol Peroxide SCHEMBL4537649 | 0.79 | PLA2G1B (0.46) | PLA2G1BMEN1KMT2AUSP2LMNA | |
| Ergosterol Peroxide SCHEMBL19715992 | 0.79 | PLA2G1B (0.46) | PLA2G1BMEN1KMT2AUSP2LMNA | |
| Ergosterol Peroxide SCHEMBL17368944 | 0.79 | PLA2G1B (0.46) | PLA2G1BMEN1KMT2AUSP2LMNA | |
| Ergosterol Peroxide SCHEMBL3281353 | 0.79 | PLA2G1B (0.46) | PLA2G1BMEN1KMT2AUSP2LMNA | |
| SCHEMBL6387074 | 0.76 | PLA2G1B (0.59) | PLA2G1BNPC1L1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853194-B2 | Sterol derivatives and their synthesis and use | Chen, Dagang (CN) | 2014-10-07 | — | — | US | disclosed |