Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543834 | 0.81 | CYP19A1 (0.44) | PGRCYP19A1SHBG | |
| SCHEMBL11795958 | 0.80 | AR (0.64) | ARPGRNR3C2CYP19A1SHBG | |
| SCHEMBL6244949 | 0.79 | AR (0.49) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL5152177 | 0.76 | AR (0.43) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL6244946 | 0.75 | AR (0.47) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL11795639 | 0.74 | AR (0.40) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL7887041 | 0.73 | AR (0.41) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL7701342 | 0.73 | AR (0.39) | ARPGRNR3C2CYP19A1MBOAT4 | |
| SCHEMBL23202655 | 0.69 | AR (0.54) | ARPGRNR3C2CYP19A1SHBG | |
| SCHEMBL7703167 | 0.69 | AR (0.54) | ARPGRNR3C2CYP19A1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523568-A2 | MICROBIOLOGICAL METHOD FOR THE PRODUCTION OF 7 ALPHA-SUBSTITUTED 11 ALPHA-HYDROXYSTEROIDS | Schering Aktiengesellschaft (DE) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004011663-A9 | MICROBIOLOGICAL METHOD FOR THE PRODUCTION OF 7 ALPHA-SUBSTITUTED 11 ALPHA-HYDROXYSTEROIDS | SCHERING AG (DE) | 2004-05-06 | — | — | WO | disclosed |
| WO-2004011663-A2 | MICROBIOLOGICAL METHOD FOR THE PRODUCTION OF 7 ALPHA-SUBSTITUTED 11 ALPHA-HYDROXYSTEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | WO | disclosed |