Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.49 |
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887041 | 0.82 | AR (0.41) | ARPGRNR3C2MBOAT4SHBG | |
| SCHEMBL7701342 | 0.82 | AR (0.39) | ARPGRNR3C2MBOAT4CYP19A1 | |
| SCHEMBL6386655 | 0.81 | AR (0.52) | ARCYP19A1 | |
| SCHEMBL4945163 | 0.81 | SHBG (0.48) | SHBGCYP19A1GRIN1GRIN2B | |
| SCHEMBL11795958 | 0.80 | AR (0.64) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL6387112 | 0.79 | AR (0.44) | ARPGRNR3C2MBOAT4SHBG | |
| SCHEMBL6244946 | 0.78 | AR (0.47) | ARPGRNR3C2MBOAT4SHBG | |
| SCHEMBL8376991 | 0.76 | AR (0.35) | ARPGRNR3C2 | |
| SCHEMBL7077217 | 0.76 | AR (0.53) | ARPGRNR3C2SHBGCYP19A1 | |
| SCHEMBL11795639 | 0.74 | AR (0.40) | ARPGRNR3C2MBOAT4SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556407-A2 | PROCESS AND INTERMEDIATES TO PREPARE 17.BETA.-HYDROXY-7.ALFA.-METHYL-19-NOR-17.ALFA.-PREGN-5(10)-EN-20-YN-3-ONE | INSTYTUT FARMACEUTYCZNY (PL) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004031204-A2 | PROCESS AND INTERMEDIATES TO PREPARE 17.BETA.-HYDROXY-7.ALFA.-METHYL-19-NOR-17.ALFA.-PREGN-5(10)-EN-20-YN-3-ONE | INSTYTUT FARMACEUTYCZNY (PL) | 2004-04-15 | — | — | WO | disclosed |