SCHEMBL6388739

SCHEMBL6388739

CC(C)CCC[C@@H](C)[C@H]1C[C@H](O)[C@H]2[C@@H]3CC=C4C(C)(C)[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ OSBP P22059 3/20 0.53
▸ USP2 O75604 2/20 0.53
▸ CYP46A1 Q9Y6A2 2/20 0.53
▸ RORC P51449 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ ABCB1 P08183 1/20 0.53
▸ OSBP2 Q969R2 1/20 0.53
▸ SRD5A1 P18405 3/20 0.47
▸ POLA1 P09884 1/20 0.45
▸ NR1H3 Q13133 1/20 0.44
▸ GRIN1 Q05586 2/20 0.44
▸ GRIN2A Q12879 2/20 0.44
▸ NPC1L1 Q9UHC9 1/20 0.43
▸ FNTA P49354 1/20 0.43
▸ FNTB P49356 1/20 0.43
▸ GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6392620 1.00 OSBP (0.53) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6388551 1.00 OSBP (0.53) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6391864 1.00 OSBP (0.53) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6387063 0.91 USP2 (0.55) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6389036 0.91 USP2 (0.55) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL7648802 0.91 USP2 (0.55) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6389903 0.91 USP2 (0.55) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL6387271 0.91 USP2 (0.55) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL7620288 0.88 OSBP (0.52) OSBPUSP2CYP46A1RORCLMNA
SCHEMBL7625157 0.88 OSBP (0.52) OSBPUSP2CYP46A1RORCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004382-A1 Meiosis regulating compounds GRONDAHL CHRISTIAN (DK) 2005-01-06 — — US disclosed
EP-0946584-B1 Meiosis regulating compounds NOVO NORDISK AS (DK) 2003-04-23 — — EP disclosed
US-6486145-B2 STEROL DERIVATIVE USEFUL IN TREATMENT OF FERTILITY NOVO NORDISK A/S (DK) 2002-11-26 — — US disclosed
US-20010005757-A1 Meiosis regulating compounds GRONDAHL CHRISTIAN (DK) 2001-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010005757-A1 Meiosis regulating compounds MNS1, NR5A1, NASP OSBP 95/4885USP2 4505/4885CYP46A1 53/4885
US-20050004382-A1 Meiosis regulating compounds NASP, MNS1, NR5A1 OSBP 95/4885USP2 4426/4885CYP46A1 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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