Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.55 |
| ▸ | OSBP | P22059 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.55 |
| ▸ | RORC | P51449 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.49 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389903 | 1.00 | USP2 (0.55) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6387271 | 1.00 | USP2 (0.55) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6389036 | 1.00 | USP2 (0.55) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6387063 | 1.00 | USP2 (0.55) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6392620 | 0.91 | OSBP (0.53) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6388551 | 0.91 | OSBP (0.53) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6391864 | 0.91 | OSBP (0.53) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6388739 | 0.91 | OSBP (0.53) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6388249 | 0.87 | RORC (0.56) | USP2OSBPLMNACYP46A1RORC | |
| SCHEMBL6389183 | 0.87 | RORC (0.56) | USP2OSBPLMNACYP46A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486145-B2 | STEROL DERIVATIVE USEFUL IN TREATMENT OF FERTILITY | NOVO NORDISK A/S (DK) | 2002-11-26 | — | — | US | disclosed |
| US-20010005757-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2001-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010005757-A1 | Meiosis regulating compounds | MNS1, NR5A1, NASP | USP2 4505/4885OSBP 95/4885LMNA 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.