SCHEMBL6389232

SCHEMBL6389232

O=S(=O)(O)c1cccc(NNc2cccc(S(=O)(=O)O)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HSD17B10 Q99714 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.50
SNCA P37840 2/20 0.49
CASR P41180 3/20 0.48
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
LMNA P02545 2/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
MAPT P10636 1/20 0.43
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
PGR P06401 1/20 0.42
NSD2 O96028 1/20 0.41
DUSP3 P51452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8752034 0.90 TSHR (0.50) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL11717248 0.88 ALDH1A1 (0.48) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL1952937 0.88 TSHR (0.48) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL10284097 0.88 ALDH1A1 (0.58) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL7073789 0.85 CASR (0.48) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL9353883 0.85 TSHR (0.53) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL892453 0.84 TSHR (0.55) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL10429490 0.84 CASR (0.45) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL3380651 0.83 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2
SCHEMBL176757 0.83 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0032784-B1 PRODUCTION OF HYDRAZOBENZENE-3,3'-DISULPHONIC ACID The Clayton Aniline Company Limited (GB) 1984-04-18 EP claimed
EP-0032784-A2 Production of hydrazobenzene-3,3'-disulphonic acid The Clayton Aniline Company Limited (GB) 1981-07-29 EP claimed
US-6908719-B1 Photosensitive compound and photosensitive composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-06-21 US disclosed
EP-0032784-B1 PRODUCTION OF HYDRAZOBENZENE-3,3'-DISULPHONIC ACID The Clayton Aniline Company Limited (GB) 1984-04-18 EP disclosed
EP-0032784-B1 PRODUCTION OF HYDRAZOBENZENE-3,3'-DISULPHONIC ACID The Clayton Aniline Company Limited (GB) 1984-04-18 EP disclosed
EP-0032784-A2 Production of hydrazobenzene-3,3'-disulphonic acid The Clayton Aniline Company Limited (GB) 1981-07-29 EP disclosed
EP-0032784-A2 Production of hydrazobenzene-3,3'-disulphonic acid The Clayton Aniline Company Limited (GB) 1981-07-29 EP disclosed
EP-0032784-A2 Production of hydrazobenzene-3,3'-disulphonic acid The Clayton Aniline Company Limited (GB) 1981-07-29 EP disclosed