Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393405 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PDCD1CD274RARBMAPT | |
| SCHEMBL6869461 | 0.91 | ALDH1A1 (0.64) | ALDH1A1PDCD1CD274RARBMAPT | |
| SCHEMBL6547348 | 0.91 | PDCD1 (0.57) | PDCD1CD274MAPT | |
| SCHEMBL6390329 | 0.88 | ALDH1A1 (0.46) | ALDH1A1RARBMAPTMEN1RARA | |
| SCHEMBL6388182 | 0.88 | ALDH1A1 (0.46) | ALDH1A1RARBMAPTMEN1RARA | |
| SCHEMBL6390327 | 0.87 | ALDH1A1 (0.46) | ALDH1A1RARBMAPT | |
| SCHEMBL6388176 | 0.87 | ALDH1A1 (0.46) | ALDH1A1RARBMAPT | |
| SCHEMBL6390324 | 0.85 | TSHR (0.45) | ALDH1A1RARBMAPTMEN1KMT2A | |
| SCHEMBL6388175 | 0.85 | TSHR (0.45) | ALDH1A1RARBMAPTMEN1KMT2A | |
| SCHEMBL29249814 | 0.84 | ALDH1A1 (0.63) | ALDH1A1RARBMAPTMEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260358-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1380567-A1 | Chiral compounds as dopants for liquid crystals | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-01-14 | — | — | EP | disclosed |