SCHEMBL6391

SCHEMBL6391

O=C(O)C1(c2ccccc2)CC1

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.83
KMT2A Q03164 4/20 0.58
TET3 O43151 1/20 0.58
FBXL19 Q6PCT2 1/20 0.58
CXXC5 Q7LFL8 1/20 0.58
TET1 Q8NFU7 1/20 0.58
KDM2B Q8NHM5 1/20 0.58
CXXC4 Q9H2H0 1/20 0.58
KDM2A Q9Y2K7 1/20 0.58
HSD11B1 P28845 2/20 0.57
HDAC4 P56524 3/20 0.53
ALOX15 P16050 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 2/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31016196 1.00 AKR1C1 (0.83) AKR1C1KMT2ATET3FBXL19CXXC5
Hydrochloric Acid SCHEMBL3866423 0.98 AKR1C1 (0.79) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL11665752 0.93 AKR1C1 (0.88) AKR1C1KMT2ATET3FBXL19CXXC5
Phenol SCHEMBL28560131 0.91 AKR1C1 (0.70) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL65167 0.91 AKR1C1 (1.00) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL1667343 0.91 AKR1C1 (0.91) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL3025596 0.89 AKR1C1 (0.68) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL8110538 0.89 AKR1C1 (0.68) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL1041902 0.89 AKR1C1 (0.96) AKR1C1KMT2ATET3FBXL19CXXC5
SCHEMBL66387 0.89 AKR1C1 (0.96) AKR1C1KMT2ATET3FBXL19CXXC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-116851483-A High-strength aluminum production process and aluminum product 广东铝派建材有限公司 2023-10-10 CN claimed
CN-112679887-B Bending-resistant silver tube and preparation method thereof 浙江新洁新材料科技有限公司 2022-04-08 CN claimed
CN-112795866-A Aluminum material and preparation method thereof 浙江贝亚特新材料股份有限公司 2021-05-14 CN claimed
CN-112679887-A Bending-resistant silver tube and preparation method thereof 浙江新洁新材料科技有限公司 2021-04-20 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
EP-2742029-B1 N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS MERCK PATENT GMBH (DE) 2016-10-05 EP claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
WO-2005058808-A1 N-SUBSTITUTED-N-SULFONYLAMINOCYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2005-06-30 WO claimed
US-20050107399-A1 Cytokine inhibitors KEMIA, INC. 2005-05-19 US claimed
WO-2005023761-A2 CYTOKINE INHIBITORS KEMIA, INC. (US) 2005-03-17 WO claimed
EP-1487824-A1 DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-12-22 EP claimed
WO-2003074515-A1 DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-09-12 WO claimed
CN-1047591-C N-substituted carbonyloxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AERICAN CYANAMID CO (US) 1999-12-22 CN claimed
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
CN-1087082-A N-substituted carbonyloxyalkylpyrrinsecticidal insecticidal, miticide and invertebrate poison AMERICAN CYANAMID CO (US) 1994-05-25 CN claimed
EP-0049977-B1 INSECTICIDAL (1,1'-BIPHENYL)-3-YLMETHYL ESTERS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM FMC Corporation (US) 1986-02-26 EP claimed
US-4255447-A Acaricidal compounds of cyclopropane carboxylic acid derivatives NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 1981-03-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS AKR1C1 4123/4885KMT2A 2681/4885TET3 2613/4885
US-20050107399-A1 Cytokine inhibitors TNF, IL1RN, IL1A AKR1C1 1145/4885KMT2A 3812/4885TET3 4326/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS AKR1C1 4123/4885KMT2A 2681/4885TET3 2613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.