Sugi Predict

Sugi Predict / Targets / IL1A

IL1A

Interleukin-1 alpha · P01583 · IL1A on Sugi Atlas →

0 patent compounds predicted against IL1A, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to IL1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effects of Fixed Space Maintainers Luting with Self-Adhesive Resin Cement on the Gingival Crevicular Fluid of Interleukin-18 Level PHASE4COMPLETED
Clinical Trial of the Use of Anakinra in Cytokine Storm Syndrome Secondary to Covid-19 (ANA-COVID-GEAS) PHASE2/PHASE3COMPLETED
Colchicine and Inflammation in Hemodialysis Patients PHASE2UNKNOWN
Management of Cytokine Storms in Severe COVID-19 Patients With Autologous Activated Platelet-rich Plasma Therapy PHASE1/PHASE2UNKNOWN
Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation PHASE1/PHASE2WITHDRAWN
Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation PHASE1/PHASE2WITHDRAWN
Ability of Curcumin to Decrease Cytokines Involved in Mucositis in the Autologous Transplant PHASE2COMPLETED
Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma PHASE2COMPLETED
The Role Of Neutrophil Proteases As Global Regulators Of Il-1 Family Cytokine Activity In Skin Disorders nanUNKNOWN
The Value of Interleukin-1β and Interleukin-33 Genetic Expression in the Pathogenesis and Differentiation of Primary ITP and SLE-Related Thrombocytopenia nanNOT_YET_RECRUITING
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery nanCOMPLETED
Acupuncture for Reduction of Inflammation nanCOMPLETED
Interleukin-34 in Stage I and II Periodontitis nanCOMPLETED
The Mechanisms and Significances of Synergistic Effects of Mycophenolic Acid and LPS on IL-1β Secretion by Mononuclear nanUNKNOWN
Role NLRP3 Inflammasome in Weight Loss Following Sleeve Gastrectomy in Morbidly Obese Patients nanUNKNOWN
Effects of Microbouts of Activity on Metabolic Health nanCOMPLETED
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions nanRECRUITING
Characteristics of Cytokine Response in Patients With Temporomandibular Disorders Treated With Occlusal Splint Therapy nanCOMPLETED
Effects of Spinal Manipulative Treatment on Inflammatory Markers in Low Back Pain Patients nanCOMPLETED
Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)? nanUNKNOWN
Post-surgery Systemic Inflammation and Neuro-immune Interactions nanCOMPLETED
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis nanCOMPLETED
Probiotics and Systemic Inflammation in Patients With Metabolic Syndrome and High Cardiovascular Risk nanWITHDRAWN
Periduroscopy: Correlation Between the Outcome of Procedure and Histological-biochemical, Neuroinflammation and Genetic Factors. nanUNKNOWN
Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis nanUNKNOWN
Study to Evaluate the Effect of Botanical Dietary Supplements on Inflammation in Healthy People nanCOMPLETED
Ketamine Versus Propofol Effect on the Immune-mediatory Response for Abdominal Surgery nanUNKNOWN
: Association of Melatonin Levels and Light and Noise Isolation in ICU nanCOMPLETED
Caspase-1 Activity, IL-1beta, and IL-18 in Patients With FMF nanNOT_YET_RECRUITING
Clinical Phenotypes in Pericarditis: IL-1RA Antibodies and suPAR Levels nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a IL1A binder may also engage these)

ProteinNameSimilarity
P08831 — 1.000 P08831 →
Q3HWU1 — 1.000 Q3HWU1 →
P79340 — 1.000 P79340 →
Q28385 — 0.999 Q28385 →
P48089 — 0.999 P48089 →
P18430 — 0.998 P18430 →
P04822 — 0.997 P04822 →
P16598 — 0.997 P16598 →
P46647 — 0.996 P46647 →
P21621 — 0.996 P21621 →
Q28579 — 0.996 Q28579 →
O46612 — 0.996 O46612 →
P79162 — 0.996 P79162 →
O46613 — 0.996 O46613 →
Q865X7 — 0.994 Q865X7 →
P79161 — 0.994 P79161 →
Q63264 — 0.994 Q63264 →
P01582 — 0.993 P01582 →
Q28386 — 0.993 Q28386 →
Q9DDT2 — 0.993 Q9DDT2 →
Q8TDB6 — 0.993 Q8TDB6 →
Q6PUD2 — 0.992 Q6PUD2 →
Q6NU51 — 0.992 Q6NU51 →
P46648 — 0.992 P46648 →
Q5U228 — 0.992 Q5U228 →
Q9XS77 — 0.992 Q9XS77 →
Q8BMD7 — 0.991 Q8BMD7 →
P26889 — 0.991 P26889 →
A4UYK8 — 0.990 A4UYK8 →
A7YDW0 — 0.990 A7YDW0 →