Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.84 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.68 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPRB | P23467 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394595 | 1.00 | PTPN1 (0.84) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6394623 | 0.88 | PTPN1 (0.80) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6394615 | 0.88 | PTPN1 (0.80) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6393832 | 0.85 | PTPN1 (1.00) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6393833 | 0.85 | PTPN1 (1.00) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6398631 | 0.85 | PTPN1 (1.00) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6238826 | 0.85 | HDAC8 (0.70) | PTPN1HDAC8 | |
| SCHEMBL6397536 | 0.84 | PTPN1 (0.80) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6397531 | 0.84 | PTPN1 (0.80) | PTPN1HDAC8PTPN2PTPRBACP1 | |
| SCHEMBL6392357 | 0.83 | PTPN1 (0.73) | PTPN1HDAC8PTPN2PTPRBACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154011-A1 | Tetrahydroisoquinolnyl sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2005-07-14 | — | — | US | claimed |
| WO-2004074256-A1 | TETRAHYDROISOQUINOLINYL SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | claimed |
| US-20050154011-A1 | Tetrahydroisoquinolnyl sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154011-A1 | Tetrahydroisoquinolnyl sulfamic acids | PTPRS, PTPRJ, PTPRM | PTPN1 9/4885HDAC8 3912/4885PTPN2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.