Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738204 | 0.89 | HDAC8 (0.60) | HDAC8PTPN1TDP1NPSR1 | |
| SCHEMBL7485383 | 0.85 | HDAC8 (0.56) | HDAC8PTPN1NPSR1CXCR3 | |
| SCHEMBL7485387 | 0.85 | HDAC8 (0.56) | HDAC8PTPN1NPSR1CXCR3 | |
| SCHEMBL9033397 | 0.85 | HDAC8 (0.53) | HDAC8PTPN1TDP1NAMPT | |
| SCHEMBL9033407 | 0.85 | HDAC8 (0.53) | HDAC8PTPN1TDP1NAMPT | |
| SCHEMBL6394595 | 0.85 | PTPN1 (0.84) | HDAC8PTPN1 | |
| SCHEMBL6394602 | 0.85 | PTPN1 (0.84) | HDAC8PTPN1 | |
| SCHEMBL11986410 | 0.84 | HDAC8 (0.53) | HDAC8PTPN1TDP1NAMPTCXCR3 | |
| SCHEMBL8295418 | 0.84 | HDAC8 (0.55) | HDAC8PTPN1TDP1 | |
| SCHEMBL6470048 | 0.84 | HDAC8 (0.55) | HDAC8PTPN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056013-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |
| EP-1541148-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2005-06-15 | — | — | EP | disclosed |