Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396562 | 1.00 | KMT2A (0.48) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL6404814 | 0.93 | ALDH1A1 (0.48) | KMT2AALDH1A1KCNH2HTR2AHTR2C | |
| SCHEMBL6404810 | 0.93 | ALDH1A1 (0.48) | KMT2AALDH1A1KCNH2HTR2AHTR2C | |
| SCHEMBL6397584 | 0.89 | GRIN2B (0.46) | ALDH1A1RAB9AKCNH2HTR2AHTR2C | |
| SCHEMBL6399855 | 0.88 | HTR2A (0.58) | KMT2AMEN1ALDH1A1KCNH2HTR2A | |
| SCHEMBL6398900 | 0.87 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1CYP2J2KDR | |
| Trifluoroacetic Acid SCHEMBL6400597 | 0.86 | HTR2A (0.44) | KMT2AALDH1A1KCNH2HTR2AHTR2C | |
| SCHEMBL6398215 | 0.84 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1KCNH2HTR2A | |
| SCHEMBL6398224 | 0.84 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1KCNH2HTR2A | |
| SCHEMBL6399721 | 0.80 | ALDH1A1 (0.62) | KMT2AALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | KMT2A 2222/4885MEN1 3773/4885ALDH1A1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.