Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL639727 | 1.00 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL640388 | 1.00 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL640301 | 1.00 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL640924 | 1.00 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL641093 | 1.00 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL639772 | 0.97 | CES2 (0.39) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL10900701 | 0.94 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL7610383 | 0.94 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL3965768 | 0.94 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL10901714 | 0.94 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969490-B1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS | BRIDGESTONE CORP (JP) | 2026-03-25 | — | — | EP | disclosed |
| US-20250389555-A1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2025-12-25 | — | — | US | disclosed |
| US-12410263-B2 | Modified high-Cis polybutadiene polymer, related methods and rubber compositions | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2025-09-09 | — | — | US | disclosed |
| US-12264232-B2 | Modified high-cis polybutadiene polymer, related methods and tire components | BRIDGESTONE CORPORATION (JP) | 2025-04-01 | — | — | US | disclosed |
| US-20250066516-A1 | HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME | BRIDGESTONE CORPORATION (JP) | 2025-02-27 | — | — | US | disclosed |
| CN-113825777-B | Modified high cis polybutadiene polymers, related methods and tire components | 株式会社普利司通 | 2025-01-28 | — | — | CN | disclosed |
| EP-4495146-A2 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | Bridgestone Americas Tire Operations, LLC (US) | 2025-01-22 | — | — | EP | disclosed |
| EP-4457250-A1 | HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME | Bridgestone Corporation (JP) | 2024-11-06 | — | — | EP | disclosed |
| EP-3966259-B1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118574860-A | Hydrogenated polybutadiene polymer and rubber composition containing the same | 株式会社普利司通 | 2024-08-30 | — | — | CN | disclosed |
| WO-2011047021-A1 | PROCESSES FOR PREPARATION OF CYCLIC ACYCLIC DIENE COPOLYMER AND RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-04-21 | — | — | WO | disclosed |
| US-20100137520-A1 | Branched Polymers and Methods for Their Synthesis and Use | BRIDGESTONE CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |
| US-7585805-B2 | polymerization catalyst containing e.g.a combination or reaction product of triisobutylaluminum an alkylating agent, Ni(II) neodecanoate borate as nickel compound, trifluoride/n-hexanol complex as F2 compound and tin tetrachloride as Cl2 compound to polymerize 1,3-butadiene to cis-1,4-polybutadiene | BRIDGESTONE CORPORATION | 2009-09-08 | — | — | US | disclosed |
| EP-2066735-A2 | BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE | Bridgestone Corporation (JP) | 2009-06-10 | — | — | EP | disclosed |
| US-20080255327-A1 | addition polymerization of conjugated polyene monomer in the presence of polymerization catalysts comprising a mixture of a nickel-containing compound, an alkylating agent, a fluorine-containing compound, a carboxylic acid and an alcohol; controlling gelation, branching and molecular weight; efficiency | BRIDGESTONE CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| WO-2008045372-A2 | BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE | BRIDGESTONE CORPORATION (JP) | 2008-04-17 | — | — | WO | disclosed |
| US-20070117942-A1 | Nickel-based catalyst composition | BRIDGESTONE CORPORATION | 2007-05-24 | — | — | US | disclosed |
| EP-1788003-A1 | Nickel-based catalyst composition | Bridgestone Corporation (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-6699813-B2 | COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS | BRIDGESTONE CORPORATION (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030176276-A1 | Lanthanide-based catalyst composition for the manufacture of polydienes | BRIDGESTONE CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250389555-A1 | MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS | MALT1, INO80C, RTCB | TSHR 1694/4885THRB 529/4885CES2 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.