Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 3/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6395754 | 0.87 | P2RY2 (0.49) | HRASP2RY2PTPN1GAPDHKMT2A | |
| SCHEMBL6393923 | 0.86 | MEN1 (0.48) | HRASP2RY2PTPN1GAPDHKMT2A | |
| SCHEMBL6396728 | 0.81 | P2RY2 (0.50) | HRASP2RY2PTPN1GAPDHKMT2A | |
| SCHEMBL6394157 | 0.81 | P2RY2 (0.49) | HRASP2RY2PTPN1GAPDHKMT2A | |
| SCHEMBL6400050 | 0.80 | P2RY2 (0.52) | HRASP2RY2PTPN1GAPDHKMT2A | |
| Benzoic Acid SCHEMBL6397602 | 0.76 | P2RY2 (0.60) | P2RY2SCDKMT2AMEN1POLB | |
| SCHEMBL11148936 | 0.73 | MEN1 (0.46) | HRASPTPN1GAPDHKMT2AMEN1 | |
| SCHEMBL7170679 | 0.73 | MEN1 (0.48) | HRASPTPN1GAPDHKMT2AMEN1 | |
| SCHEMBL6394999 | 0.72 | P2RY2 (0.65) | P2RY2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19619197 | 0.72 | USP2 (0.55) | HRASPTPN1GAPDHKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | CELLTECH R & D LIMITED (GB) | 2005-01-13 | — | — | US | disclosed |
| EP-1409503-A1 | NON-NATURAL CARBON-LINKED NUCLEOTIDES AND DINUCLEOTIDES | Celltech R & D Limited (GB) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003011885-A1 | NON-NATURAL CARBON-LINKED NUCLEOTIDES AND DINUCLEOTIDES | CELLTECH R & D LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | P2RY1, P2RY11, P2RY13 | HRAS 1321/4885P2RY2 4/4885SCD 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.