Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NCS1 | P62166 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396728 | 0.89 | P2RY2 (0.50) | P2RY2MEN1KMT2AUSP2POLB | |
| SCHEMBL6393923 | 0.86 | MEN1 (0.48) | P2RY2MEN1KMT2AUSP2POLB | |
| SCHEMBL6395754 | 0.81 | P2RY2 (0.49) | P2RY2MEN1KMT2AUSP2POLB | |
| SCHEMBL6397605 | 0.80 | HRAS (0.53) | P2RY2MEN1KMT2AUSP2POLB | |
| Benzoic Acid SCHEMBL6400046 | 0.76 | P2RY2 (0.60) | P2RY2AKR1B1DYRK1ANCS1AKR1A1 | |
| SCHEMBL6394157 | 0.75 | P2RY2 (0.49) | P2RY2MEN1KMT2AUSP2POLB | |
| SCHEMBL7170679 | 0.73 | MEN1 (0.48) | MEN1KMT2AUSP2POLBPTPN1 | |
| SCHEMBL6395433 | 0.72 | P2RY2 (0.84) | P2RY2AKR1B1DYRK1ANCS1 | |
| SCHEMBL11148936 | 0.71 | MEN1 (0.46) | MEN1KMT2AUSP2POLBPTPN1 | |
| SCHEMBL6252668 | 0.71 | PTPN1 (0.68) | MEN1KMT2AUSP2POLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | CELLTECH R & D LIMITED (GB) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009777-A1 | Non-natural carbon-linked nucleotides and dinucleotides | P2RY1, P2RY11, P2RY13 | P2RY2 4/4885MEN1 1789/4885KMT2A 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.