Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30906969 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117344 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL264832 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL264639 | 0.89 | — | — | |
| SCHEMBL491198 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117312 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117388 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117329 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117292 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL31136005 | 0.89 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939923-B2 | Resin for solid phase synthesis | ROHM AND HAAS COMPANY (US) | 2005-09-06 | — | — | US | disclosed |
| EP-1452538-A1 | Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto | ROHM AND HAAS COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1403290-A1 | Resin for solid phase synthesis | Rohm and Haas (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-1394196-A1 | Resin for solid phase synthesis | ROHM AND HAAS COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |