Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515423 | 1.00 | TSHR (0.44) | TSHRMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL11094685 | 0.79 | TSHR (0.30) | TSHRALDH1A1TDP1 | |
| SCHEMBL11093541 | 0.79 | TSHR (0.30) | TSHRALDH1A1TDP1 | |
| SCHEMBL5132296 | 0.78 | TSHR (0.50) | TSHRMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL6536885 | 0.77 | ECE1 (0.34) | HPGDALDH1A1TDP1LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL11449331 | 0.76 | TSHR (0.49) | TSHRMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL7341604 | 0.76 | TSHR (0.44) | TSHRMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL2964153 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL10490865 | 0.73 | — | — | |
| SCHEMBL8500057 | 0.73 | TSHR (0.46) | TSHRMEN1HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102659643-B | A kind of by α, beta-unsaturated acyl amine prepares the method replacing Homotaurine | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2015-10-14 | — | — | CN | disclosed |
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | TSHR 2489/4885MEN1 3773/4885HPGD 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.