Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11449331 | 0.98 | TSHR (0.49) | TSHRMEN1HPGDKMT2ASLC22A6 | |
| SCHEMBL27515423 | 0.78 | TSHR (0.44) | TSHRMEN1HPGDKMT2ATDP1 | |
| SCHEMBL6398798 | 0.78 | TSHR (0.44) | TSHRMEN1HPGDKMT2ATDP1 | |
| SCHEMBL7341604 | 0.78 | TSHR (0.44) | TSHRMEN1HPGDKMT2ATDP1 | |
| SCHEMBL29009323 | 0.76 | GABRP (0.48) | TSHRMEN1HPGDKMT2A | |
| SCHEMBL2858121 | 0.76 | SLC22A6 (0.43) | TSHRSLC22A6TDP1ALDH1A1CACNA2D1 | |
| SCHEMBL4817481 | 0.76 | SLC22A6 (0.43) | TSHRSLC22A6TDP1ALDH1A1CACNA2D1 | |
| SCHEMBL4419642 | 0.75 | NOS3 (0.46) | TSHRSLC22A6TDP1CACNA2D1CACNB3 | |
| SCHEMBL8500057 | 0.75 | TSHR (0.46) | TSHRMEN1HPGDKMT2ATDP1 | |
| SCHEMBL8500054 | 0.75 | TSHR (0.46) | TSHRMEN1HPGDKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620494-B1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | CONSEJO SUPERIOR DE INVESTIG CIENTÍFICAS (CSIC) (ES) | 2017-02-22 | — | — | EP | claimed |
| US-20130274510-A1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-10-17 | — | — | US | claimed |
| EP-2620494-A1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2013-07-31 | — | — | EP | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| EP-2620494-B1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | CONSEJO SUPERIOR DE INVESTIG CIENTÍFICAS (CSIC) (ES) | 2017-02-22 | — | — | EP | disclosed |
| US-20130274510-A1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-10-17 | — | — | US | disclosed |
| EP-2620494-A1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2013-07-31 | — | — | EP | disclosed |
| US-20060264483-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2006-11-23 | — | — | US | disclosed |
| US-7045518-B2 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20040267022-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G. D. SEARLE & CO. | 2004-12-30 | — | — | US | disclosed |
| EP-1462443-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfamic acids useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-1994004493-A1 | SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | disclosed |
| US-4352753-A | 3-[[(2,3-Dihydro-1H-indol-2-yl)carbonyl]thio]propanoic (and acetic) acids as intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| US-4256761-A | Antihypertensive amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4186268-A | Mercaptoacylpyrrolidine phosphonic acids and related compounds | E. R. SQUIBB & SONS, INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4141734-A | SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS | CIBA-GEIBY AG (CH) | 1979-02-27 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4046889-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANGIOTENSIN CONVERSION | E. R. SQUIBB & SONS, INC. (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267022-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | DNPEP, PRSS1, TMPRSS15 | TSHR 4704/4885MEN1 4621/4885HPGD 1698/4885 |
| US-20130274510-A1 | SYNTHESIS OF POLYHYDROXYALKANOATES (PHA) WITH THIOESTER GROUPS IN THE SIDE CHAIN | COASY, FADS1, ABHD5 | TSHR 3334/4885MEN1 4404/4885HPGD 593/4885 |
| US-20060264483-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | DNPEP, PREP, PRSS1 | TSHR 4711/4885MEN1 4502/4885HPGD 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.