Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399327 | 1.00 | TDP1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL4965365 | 1.00 | TDP1 (0.47) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9390114 | 0.83 | ELANE (0.59) | TDP1 | |
| SCHEMBL9390111 | 0.83 | ELANE (0.59) | TDP1 | |
| SCHEMBL9385789 | 0.83 | ELANE (0.43) | — | |
| SCHEMBL9385796 | 0.83 | ELANE (0.43) | — | |
| SCHEMBL9385650 | 0.83 | ELANE (0.47) | — | |
| SCHEMBL9385648 | 0.83 | ELANE (0.47) | — | |
| SCHEMBL9384795 | 0.82 | ELANE (0.44) | — | |
| SCHEMBL10832933 | 0.81 | ALDH1A1 (0.43) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| CN-1048494-C | Process for preparing carbapenen and penem compounds and new compounds involved in that process | SANKYO CO (JP) | 2000-01-19 | — | — | CN | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| CN-1094728-A | Prepare the method for carbapeneme and penem and the new compound that relates to | SANKYO CO (JP) | 1994-11-09 | — | — | CN | disclosed |
| US-4290948-A | 2-THIOSUBSTITUTED PENICILLINS | BEECHAM GROUP LIMITED (GB) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | TDP1 4736/4885ATM 3200/4885ALDH1A1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.