Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6399435

O=C(O)C(F)(F)F.O=C(S[C@H]1CCNC1)c1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 10/20 0.41
SLC6A4 P31645 10/20 0.41
SLC6A3 Q01959 5/20 0.41
CES1 P23141 1/20 0.38
KMT2A Q03164 1/20 0.37
SSTR1 P30872 1/20 0.37
SSTR4 P31391 1/20 0.37
CHRM4 P08173 1/20 0.36
CYP3A4 P08684 1/20 0.36
CHRM5 P08912 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6405588 1.00 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3CES1KMT2A
SCHEMBL8759876 0.91 KMT2A (0.42) SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL6397894 0.91 KMT2A (0.42) SLC6A2SLC6A4SLC6A3KMT2A
Trifluoroacetic Acid SCHEMBL21640637 0.88 CES1 (0.42) SLC6A2SLC6A4SLC6A3CES1CYP3A4
SCHEMBL27838683 0.78 CHRNB2 (0.46) SLC6A2SLC6A4SLC6A3CES1
SCHEMBL12021655 0.76 CHRNB2 (0.47) KMT2A
Trifluoroacetic Acid SCHEMBL6879701 0.72 KDM1A (0.41) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL6875842 0.72 KDM1A (0.41) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL9687612 0.71 CHEK1 (0.40) SLC6A2SLC6A4SLC6A3CES1KMT2A
Trifluoroacetic Acid SCHEMBL8758752 0.70 CES1 (0.31) CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same DAIICHI SUNTORY PHARMA CO., LTD. (JP) 2005-01-06 US disclosed
EP-0757051-B1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-10-29 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same MRPL21, MRPS2, MRPS28 SLC6A2 3194/4885SLC6A4 3085/4885SLC6A3 4010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.