Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CAD | P27708 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399581 | 1.00 | NPSR1 (0.44) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL4454382 | 1.00 | NPSR1 (0.44) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL4446758 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL6504169 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL6504174 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL6504164 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL4446753 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL4446761 | 0.86 | NPSR1 (0.42) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL2647184 | 0.81 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1MAPT | |
| SCHEMBL2647130 | 0.81 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124668-A1 | Amino acids with affinity for the alpha2delta-protein | WARNER-LAMBERT COMPANY LLC | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124668-A1 | Amino acids with affinity for the alpha2delta-protein | SCN2A, SCN1A, OPRD1 | NPSR1 580/4885ALOX15 4381/4885HCAR2 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.