Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400906 | 0.94 | LSS (0.37) | LSSTP53LMNAMAPTHRH3 | |
| SCHEMBL6400289 | 0.90 | MAPT (0.41) | LSSTP53LMNAMAPTHRH3 | |
| SCHEMBL6403698 | 0.88 | MAPT (0.37) | LSSTP53LMNAMAPTHRH3 | |
| SCHEMBL6401256 | 0.87 | LSS (0.45) | LSSHRH3MEN1KMT2A | |
| SCHEMBL6403927 | 0.87 | MAPT (0.40) | LSSTP53LMNAMAPTMEN1 | |
| SCHEMBL6403822 | 0.86 | LSS (0.47) | LSSHRH3MEN1KMT2A | |
| SCHEMBL6400492 | 0.86 | LSS (0.47) | LSSHRH3MEN1KMT2A | |
| SCHEMBL5635668 | 0.85 | HRH3 (0.41) | LSSTP53MAPTHRH3RORC | |
| SCHEMBL5638296 | 0.84 | MAPT (0.47) | LSSTP53LMNAMAPT | |
| SCHEMBL6403814 | 0.84 | NLRP3 (0.41) | LSSTP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603872-A1 | S-[2-[(1-IMINOETHYL)AMINO]ETHYL]-2-METHYL-L-CYSTEINE MALEATE HYDROCHLORIDE CRYSTALLINE SALT | Pharmacia Corporation (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080956-A1 | S-[2-[(1-IMINOETHYL)AMINO]ETHYL]-2-METHYL-L-CYSTEINE MALEATE HYDROCHLORIDE CRYSTALLINE SALT | PHARMACIA CORPORATION (US) | 2004-09-23 | — | — | WO | disclosed |