Phthalimide

Phthalimide

SCHEMBL64

O=C1NC(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 1.00
CASP7 P55210 3/20 0.79
CASP3 P42574 2/20 0.79
CASP6 P55212 2/20 0.79
CASP8 Q14790 2/20 0.79
CASP2 P42575 1/20 0.79
PARP1 P09874 4/20 0.59
PDGFRA P16234 1/20 0.59
FER P16591 1/20 0.59
LTK P29376 1/20 0.59
CDK8 P49336 1/20 0.59
ACVR1 Q04771 1/20 0.59
LRRK2 Q5S007 1/20 0.59
DYRK1B Q9Y463 1/20 0.59
MAPK1 P28482 4/20 0.54
LMNA P02545 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HSD17B10 Q99714 1/20 0.54
MAOA P21397 5/20 0.52
MAOB P27338 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL7771670 1.00 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL30125197 1.00 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL29366030 1.00 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 1.00 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL11040503 1.00 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL228977 0.97 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL1205294 0.97 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10436667 0.97 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL165345 0.97 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL5742518 0.97 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 87931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747287-A1 METHOD FOR FUNCTIONALISING POLYOLEFINS VIA THE INTRODUCTION OF AN OXIME FUNCTION UNIVERSITE DE BORDEAUX (FR) 2026-05-27 EP claimed
CN-121136036-B Hair fixing reinforcing soft gasket material and application thereof in plush toy Dongguan Yunheng Plastic Products Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12637534-B2 Imide-containing polyester polyols and intumescent rigid foams STEPAN COMPANY (US) 2026-05-26 US claimed
CN-121873631-B Spin-on carbon composition, semiconductor preparation method and semiconductor device Jiageng Innovation Laboratory (CN) 2026-05-26 CN claimed
CN-117487536-B Double-shell thermochromic microcapsule as well as preparation method and application thereof Wuhan Zhongke Advanced Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12636370-B2 Combination therapy for treatment of cancer INSTITUTE FOR CANCER RESEARCH (US) 2026-05-26 US claimed
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 US claimed
EP-4743555-A1 PHTHALIMIDE COMPOUNDS AS BASE OIL FOR LUBRICANT COMPOSITIONS Klueber Lubrication München GmbH & Co. KG (DE) 2026-05-20 EP claimed
CN-117209426-B Nitidine-like sulfonamide derivative and preparation method and application thereof 广西中医药大学 2026-05-19 CN claimed
CN-121758308-B Preparation method of L-2, 4-diaminobutyric acid dihydrochloride 山东省农药科学研究院 2026-05-19 CN claimed
US-3956241-A CHROMIUM(III) CHELATE COMPOUND AEROJET-GENERAL CORPORATION (US) 1976-05-11 US claimed
US-3953168-A Dyeing process SANDOZ LTD. (CH) 1976-04-27 US claimed
US-3948659-A BLEACHING FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US claimed
US-3947374-A Substituted halotriazines as peroxygen bleach activators AMERICAN CYANAMID COMPANY (US) 1976-03-30 US claimed
US-3947466-A ANTIDEPRESSANTS, ANTIANXIETY THE UPJOHN COMPANY (US) 1976-03-30 US claimed
US-3944598-A Production of amine salts of carboxylic acids THE LUMMUS COMPANY (US) 1976-03-16 US claimed
US-3941779-A Method for producing 2-(substituted thio)-3-cephem derivatives E. R. SQUIBB & SONS, INC. (US) 1976-03-02 US claimed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US claimed
US-3932546-A Preparation of polyenes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1976-01-13 US claimed
US-3931243-A Production of phthalic anhydride THE LUMMUS COMPANY (US) 1976-01-06 US claimed