Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 3/20 | 0.79 |
| ▸ | CASP3 | P42574 | 2/20 | 0.79 |
| ▸ | CASP6 | P55212 | 2/20 | 0.79 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.79 |
| ▸ | CASP2 | P42575 | 1/20 | 0.79 |
| ▸ | PARP1 | P09874 | 4/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | FER | P16591 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL7771670 | 1.00 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL30125197 | 1.00 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL29366030 | 1.00 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL10192661 | 1.00 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL64 | 1.00 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL228977 | 0.97 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL1205294 | 0.97 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL10436667 | 0.97 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL165345 | 0.97 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL5742518 | 0.97 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117645-A | The poly- fragrant acid imide manufacturing method of one kind and its process units | 梅雪 | 2018-06-05 | — | — | CN | disclosed |
| CN-105916842-A | Preparation method of 2-alkyl-3, 3-bis (hydroxyaryl) phthalimidine | 沙特基础工业全球技术有限公司 | 2016-08-31 | — | — | CN | disclosed |
| WO-2014031872-A2 | SMALL MOLECULE INHIBITORS FOR TREATING PARASITIC INFECTIONS | THE BROAD INSTITUTE, INC. (US) | 2014-02-27 | — | — | WO | disclosed |
| CN-103221039-A | Airway administration of angiogenesis inhibitors | DANISH MEDICAL CONSULTS APS | 2013-07-24 | — | — | CN | disclosed |
| CN-101951901-B | Use of phthalimide derivatives in the treatment of diseases | UNICAMP | 2012-11-28 | — | — | CN | disclosed |
| CN-101951901-A | The application of phthalimide derivant in the treatment disease | UNICAMP | 2011-01-19 | — | — | CN | disclosed |
| US-4444264-A | PHTHALIMIDE PARTICLES | HALLIBURTON COMPANY (US) | 1984-04-24 | — | — | US | disclosed |