Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844006 | 0.87 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL5843223 | 0.87 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5844489 | 0.86 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5844690 | 0.80 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5844603 | 0.80 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL5844698 | 0.80 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL5845265 | 0.80 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5844139 | 0.79 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL5844294 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5845264 | 0.77 | CRHR1 (0.55) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956047-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-10-18 | — | — | US | disclosed |