Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 20/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 20/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399496 | 0.91 | CHRM2 (0.52) | CHRM2CHRM1CHRM3 | |
| Bromide SCHEMBL4523960 | 0.80 | CHRM2 (0.45) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6399750 | 0.80 | CHRM2 (0.57) | CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL6400216 | 0.79 | CHRM2 (0.49) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6398785 | 0.79 | CHRM2 (0.68) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6399727 | 0.78 | CHRM2 (0.61) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6399675 | 0.78 | CHRM2 (0.68) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6398771 | 0.78 | CHRM2 (0.60) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6400127 | 0.78 | CHRM2 (0.60) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6404269 | 0.77 | CHRM2 (0.63) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054696-A1 | Indole compounds and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-10 | — | — | US | claimed |
| EP-1452526-A1 | INDOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | claimed |
| US-20050054696-A1 | Indole compounds and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-10 | — | — | US | disclosed |
| US-6846835-B2 | Treating chronic obstructive pulmonary disease, chronic bronchitis, asthma, chronic respiratory tract obstruction, fibroid lung, pulmonary emphysema or rhinitis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-01-25 | — | — | US | disclosed |
| EP-1452526-A1 | INDOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-20030191316-A1 | Ester derivatives | MSD K.K. (JP) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191316-A1 | Ester derivatives | CHRM3, CHRM2, CHRM1 | CHRM2 2/4885CHRM1 3/4885CHRM3 1/4885 |
| US-20050054696-A1 | Indole compounds and medicinal use thereof | IDO1, GPR119, SLC5A1 | CHRM2 1479/4885CHRM1 1610/4885CHRM3 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.