Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1265183 | 0.85 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL3485710 | 0.84 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL30148162 | 0.83 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL615409 | 0.83 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1110533 | 0.82 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1110483 | 0.82 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1110574 | 0.82 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1110528 | 0.82 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL4445663 | 0.81 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28322333 | 0.81 | MAPT (0.69) | MAPTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130961-A1 | Muscarinic M1 receptor agonists for pain management | ACADIA PHARMACEUTICALS INC. | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130961-A1 | Muscarinic M1 receptor agonists for pain management | CHRM1, CHRM3, CHRM2 | MAPT 2485/4885ALDH1A1 1477/4885MEN1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.