Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010106 | 0.95 | ALK (0.30) | ALK | |
| SCHEMBL1009643 | 0.91 | ALK (0.35) | ALKMEN1LMNATSHRKMT2A | |
| SCHEMBL3704719 | 0.88 | MEN1 (0.31) | ALKMEN1LMNATSHRKMT2A | |
| SCHEMBL30708919 | 0.88 | MEN1 (0.31) | ALKMEN1LMNATSHRKMT2A | |
| SCHEMBL1009814 | 0.87 | FFAR1 (0.33) | ALK | |
| SCHEMBL1009670 | 0.87 | KDM4E (0.36) | ALKMEN1LMNATSHRKMT2A | |
| SCHEMBL1009637 | 0.86 | ALK (0.32) | ALKMAPTKDM4E | |
| SCHEMBL8510608 | 0.85 | MEN1 (0.32) | ALKMEN1LMNATSHRKMT2A | |
| SCHEMBL25529849 | 0.85 | KDM4E (0.35) | MEN1LMNATSHRKMT2AMAPT | |
| SCHEMBL13988246 | 0.84 | ALK (0.40) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050258408-A1 | Photochromic contact lenses and methods for their production | MOLOCK FRANK F | 2005-11-24 | — | — | US | disclosed |