Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30708919 | 0.97 | MEN1 (0.31) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL3704719 | 0.97 | MEN1 (0.31) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL2371469 | 0.94 | ALK (0.32) | HTTPDK2RECQLALKGPR84 | |
| SCHEMBL26231110 | 0.93 | PDK2 (0.31) | PDK2ALK | |
| SCHEMBL1009643 | 0.93 | ALK (0.35) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL15954429 | 0.92 | ALDH1A1 (0.32) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL25606724 | 0.91 | KDM4E (0.36) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL1009814 | 0.90 | FFAR1 (0.33) | ALKGPR84 | |
| SCHEMBL25717698 | 0.90 | KDM4E (0.35) | MEN1LMNATSHRKMT2AKDM4E | |
| SCHEMBL29453316 | 0.89 | LMNA (0.32) | LMNAPDK2MAPTALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647538-B2 | Photochromic compounds having at least two photochromic moieties | TRANSITIONS OPTICAL, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-20120136148-A1 | Photochromic Compounds Having At Least Two Photochromic Moieties | TRANSITIONS OPTICAL, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136148-A1 | Photochromic Compounds Having At Least Two Photochromic Moieties | CRY2, PCNA, MTCL3 | MEN1 1225/4885LMNA 1232/4885TSHR 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.