Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.48 |
| ▸ | INSR | P06213 | 3/20 | 0.48 |
| ▸ | TEK | Q02763 | 3/20 | 0.48 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 9/20 | 0.44 |
| ▸ | CHUK | O15111 | 5/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724072 | 0.88 | KDR (0.49) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6402149 | 0.80 | KDR (0.47) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6401975 | 0.78 | KDR (0.47) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6394323 | 0.76 | KDR (0.47) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6313981 | 0.75 | KDR (0.45) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6729223 | 0.71 | KDR (0.57) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6404350 | 0.71 | KDR (0.54) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6728908 | 0.71 | KDR (0.54) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6396399 | 0.70 | IKBKB (0.39) | KDRINSRTEKCSF1RPDGFRB | |
| SCHEMBL6399454 | 0.70 | KDR (0.65) | KDRINSRTEKCSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549645-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | Johnson & Johnson Pharmaceutical Research & Development, Inc. (US) | 2005-07-06 | — | — | EP | claimed |
| WO-2004031184-A1 | 4,6-DIAMINOSUBSTITUTED-2-[OXY OR AMINOXY]-[1,3,5]TRIAZINES AS PROTEIN TYROSINE KINASE INHIBITORS | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. (US) | 2004-04-15 | — | — | WO | claimed |