Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396908 | 0.91 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6399247 | 0.90 | KDM4E (0.47) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6396905 | 0.80 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6406321 | 0.78 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6756905 | 0.76 | MAPT (0.48) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL23216669 | 0.75 | KDM4E (0.48) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL29768426 | 0.75 | KDM4E (0.48) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL6399926 | 0.73 | IDO1 (0.45) | MAPTCYP1A2HSD17B10THRB | |
| SCHEMBL7103882 | 0.73 | MAPT (0.45) | KDM4EMAPTALDH1A1NPSR1MEN1 | |
| SCHEMBL2771455 | 0.73 | KDM4E (0.50) | KDM4EMAPTALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2005-03-03 | — | — | US | claimed |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-01-15 | — | — | US | claimed |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2002-08-15 | — | — | US | claimed |
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2005-03-03 | — | — | US | disclosed |
| US-6838583-B2 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and the methods of using the same | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1409443-A2 | NON-HALOGENATED NAPHTHOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | WARNER-LAMBERT COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-01-15 | — | — | US | disclosed |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER DAVID SCOTT (US) | 2002-08-15 | — | — | US | disclosed |
| WO-2002050001-A2 | NON-HALOGENATED NAPHTHOL COMPOUNDS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME | WARNER-LAMBERT COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049306-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | KDM4E 4695/4885MAPT 3735/4885ALDH1A1 3207/4885 |
| US-20040010046-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | KDM4E 4695/4885MAPT 3735/4885ALDH1A1 3207/4885 |
| US-20020110530-A1 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and methods of using the same | NPM1, NOC2L, NAF1 | KDM4E 4695/4885MAPT 3735/4885ALDH1A1 3207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.