Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346454 | 0.77 | SOS2 (0.63) | SOS2SRCCTSBNQO1MET | |
| SCHEMBL906658 | 0.76 | SOS2 (1.00) | SOS2SRCCTSBPLAUNCF1 | |
| SCHEMBL11036934 | 0.76 | SOS2 (0.62) | SOS2SRCNQO1KDM4EMAPT | |
| SCHEMBL30824469 | 0.76 | SOS2 (0.62) | SOS2SRCSLC40A1CTSBNQO1 | |
| SCHEMBL4771863 | 0.76 | SOS2 (0.62) | SOS2SRCSLC40A1CTSBNQO1 | |
| SCHEMBL3578542 | 0.76 | SOS2 (0.62) | SOS2SRCSLC40A1CTSBNQO1 | |
| SCHEMBL13977559 | 0.76 | SOS2 (0.62) | SOS2SRCSLC40A1CTSBNQO1 | |
| Hydrochloric Acid SCHEMBL3587293 | 0.74 | SOS2 (0.61) | SOS2SRCSLC40A1CTSBNQO1 | |
| SCHEMBL6431724 | 0.74 | SOS2 (0.96) | SOS2SRCCTSBPLAUNCF1 | |
| SCHEMBL6401338 | 0.74 | SOS2 (0.96) | SOS2SRCCTSBPLAUNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921589-B2 | Electroluminescent elements | TORAY INDUSTRIES, INC. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20020160227-A1 | Electroluminescent elements | KOHAMA AKIRA (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1000998-B1 | Electroluminescent element and devices | TORAY INDUSTRIES (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-1000998-A1 | Electroluminescent element and devices | TORAY INDUSTRIES, INC. (JP) | 2000-05-17 | — | — | EP | disclosed |