SCHEMBL906658

SCHEMBL906658

N#Cc1ccc2cccc(O)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 1.00
SRC P12931 1/20 0.54
METAP2 P50579 2/20 0.53
PLAU P00749 1/20 0.53
NCF1 P14598 1/20 0.53
ALOX12 P18054 3/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KDM4E B2RXH2 5/20 0.49
KMT2A Q03164 4/20 0.49
PIM1 P11309 1/20 0.47
TSHR P16473 2/20 0.47
MMP2 P08253 1/20 0.47
CHRM1 P11229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6431724 0.98 SOS2 (0.96) SOS2SRCMETAP2PLAUNCF1
SCHEMBL6401338 0.98 SOS2 (0.96) SOS2SRCMETAP2PLAUNCF1
SCHEMBL2516025 0.84 SOS2 (0.72) SOS2METAP2PLAUNCF1ALOX12
SCHEMBL5346454 0.79 SOS2 (0.63) SOS2SRCCTSBRAB9A
SCHEMBL10649714 0.78 SOS2 (0.64) SOS2METAP2PLAUNCF1ALOX12
SCHEMBL30824469 0.77 SOS2 (0.62) SOS2SRCALDH1A1HPGDKDM4E
SCHEMBL3578542 0.77 SOS2 (0.62) SOS2SRCPLAUNCF1ALDH1A1
SCHEMBL13977559 0.77 SOS2 (0.62) SOS2SRCPLAUCYP3A4HIF1A
SCHEMBL4771863 0.77 SOS2 (0.62) SOS2SRCCYP1A2CTSBLMNA
SCHEMBL11036934 0.77 SOS2 (0.62) SOS2SRCALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118419995-A Quaternary sodium-electricity monocrystal precursor and preparation method and application thereof 格林美股份有限公司 2024-08-02 CN claimed
EP-2265677-B1 CORROSION DETECTION PRODUCT AND METHOD BATTELLE MEMORIAL INSTITUTE (US) 2019-05-15 EP claimed
US-8501595-B2 Thin film containing nanocrystal particles and method for preparing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-08-06 US claimed
US-7633087-B2 Semiconductor thin film using self-assembled monolayers and methods of production thereof SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2009-12-15 US claimed
US-20070298160-A1 THIN FILM CONTAINING NANOCRYSTAL PARTICLES AND METHOD FOR PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-12-27 US claimed
US-20070166645-A1 Chalcogenide precursor compound and method for preparing chalcogenide thin film using the same SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2007-07-19 US claimed
US-20070117279-A1 Semiconductor thin film using self-assembled monolayers and methods of production thereof CORNING PRECISION MATERIALS CO., LTD. (KR) 2007-05-24 US claimed
US-20070090346-A1 Porous chalcogenide thin film, method for preparing the same and electronic device using the same SAMSUNG CORNING PRECISION GLASS CO., LTD. (KR) 2007-04-26 US claimed
CN-118978522-A Synthesis method of 2-substituted-4-hydroxy-2-thiazoline derivative 信阳师范学院 2024-11-19 CN disclosed
CN-118419995-A Quaternary sodium-electricity monocrystal precursor and preparation method and application thereof 格林美股份有限公司 2024-08-02 CN disclosed
US-11701374-B1 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression SIERRA SCIENCES, INC. (US) 2023-07-18 US disclosed
US-11701374-B1 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression SIERRA SCIENCES, INC. (US) 2023-07-18 US disclosed
US-20210395243-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2021-12-23 US disclosed
CN-113166070-A Pesticidal compounds 巴斯夫欧洲公司 2021-07-23 CN disclosed
EP-0392803-A1 Novel compounds Beecham Group p.l.c. (GB) 1990-10-17 EP disclosed
EP-0308757-A1 Multidentate chelators based on the 8-hydroxyquinoline unit ABBOTT LABORATORIES (US) 1989-03-29 EP disclosed
EP-0125276-A1 NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS HÖGBERG, Sverker (SE) 1984-11-21 EP disclosed
EP-0124577-A1 NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS HÖGBERG, Sverker (SE) 1984-11-14 EP disclosed
WO-1984001947-A1 NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS HOEGBERG SVERKER 1984-05-24 WO disclosed
WO-1984001946-A1 NEW CHELATE FORMING BISQUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS HOEGBERG SVERKER 1984-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701374-B1 8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression TERT, TERF2, RNGTT SOS2 3602/4885SRC 4466/4885METAP2 1330/4885
US-20210395243-A1 PESTICIDAL COMPOUNDS NIT2, PNMT, DDT SOS2 3374/4885SRC 2382/4885METAP2 1051/4885
US-20070090346-A1 Porous chalcogenide thin film, method for preparing the same and electronic device using the same STOM, PROX1, HCN4 SOS2 1689/4885SRC 1199/4885METAP2 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.