Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.55 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891727 | 0.90 | GRIK1 (0.64) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| SCHEMBL13675503 | 0.87 | CHRM1 (0.39) | GRIK1GRIK2CPA1CHRM1AKR1A1 | |
| SCHEMBL1045275 | 0.86 | GRIK1 (0.57) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| SCHEMBL6050002 | 0.82 | GRIK1 (0.75) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| SCHEMBL10349627 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| SCHEMBL10349629 | 0.80 | GRIK1 (0.46) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| Pentanal SCHEMBL11495781 | 0.78 | TSHR (0.50) | GRIK1GRIK2CPA1CHRM1AKR1A1 | |
| SCHEMBL10625605 | 0.78 | — | — | |
| SCHEMBL5133412 | 0.77 | GRIK1 (0.47) | GRIK1GRIK2CPA1CYP2C19TBXAS1 | |
| SCHEMBL24215021 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2CPA1CYP2C19ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549278-A4 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1549278-A2 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | disclosed |
| EP-1142894-B1 | Volatile precursors for deposition of metals and metal-containing films | AIR PROD & CHEM (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6818783-B2 | HOMOLOGOUS EIGHT MEMBERED RING COMPOUNDS HAVING A METAL, SUCH AS COPPER, REVERSIBLY BOUND IN THE RING AND CONTAINING CARBON, NITROGEN, SILICON AND/OR OTHER METALS. | AIR PRODUCTS AND CHEMICALS, INC. | 2004-11-16 | — | — | US | disclosed |
| US-20040215030-A1 | Precursors for metal containing films | VERSUM MATERIALS US, LLC | 2004-10-28 | — | — | US | disclosed |
| EP-1471568-A1 | Precursors for metal containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2004012684-A2 | M3MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2003-07-17 | — | — | US | disclosed |
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2002-01-31 | — | — | US | disclosed |
| EP-1142894-A2 | Volatile precursors for deposition of metals and metal-containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5091559-A | Process for the preparation of alkyl 4-oxobutyrate and its acetals | QUANTUM CHEMICAL CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | GRIK1 2698/4885GRIK2 3156/4885CPA1 4448/4885 |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | GRIK1 2778/4885GRIK2 3236/4885CPA1 4428/4885 |
| US-20040215030-A1 | Precursors for metal containing films | TBL3, TBL2, TNNI3 | GRIK1 3730/4885GRIK2 3718/4885CPA1 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.