Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404074 | 0.89 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6405817 | 0.88 | POLB (0.48) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6401580 | 0.86 | POLB (0.49) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6405222 | 0.85 | SMN1; SMN2 (0.59) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6403827 | 0.78 | POLB (0.65) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6405551 | 0.77 | KMT2A (0.41) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6409368 | 0.77 | TDP1 (0.52) | POLBSMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL6405202 | 0.77 | HSP90AA1 (0.47) | POLBSMN1; SMN2JAK2ALDH1A1HTT | |
| SCHEMBL6406614 | 0.77 | NAMPT (0.48) | POLBSMN1; SMN2L3MBTL1LMNARAB9A | |
| SCHEMBL6403903 | 0.77 | PPARG (0.55) | POLBSMN1; SMN2LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | POLB 3713/4885SMN1; SMN2 4458/4885JAK2 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.