SCHEMBL6403066

SCHEMBL6403066

CCN(CC)c1c[c]c2c(c1)Oc1cc(N(CC)CC)ccc1C2c1ccc(S(=O)(=O)O)cc1S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
HTT P42858 1/20 0.35
CASP7 P55210 1/20 0.35
HBB P68871 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699608 0.89 MEN1 (0.40) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL16490263 0.84 MEN1 (0.39) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL3844704 0.78 CNR2 (0.38) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL17264739 0.77 MEN1 (0.33) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL3839170 0.77 MEN1 (0.36) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL3839806 0.77 KMT2A (0.37) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL3840387 0.77 HTT (0.41) MEN1KMT2ASMN1; SMN2CYP2C9CYP2C19
SCHEMBL3843291 0.76 CA12 (0.37) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL17626410 0.75 MEN1 (0.34) MEN1KMT2AGAASMN1; SMN2CYP2C9
SCHEMBL6402835 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050058602-A1 Dye composition and method for detection of demineralized lesions in teeth THE PROCTER & GAMBLE COMPANY 2005-03-17 US disclosed