SCHEMBL3840387

SCHEMBL3840387

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C2c1ccc(S(=O)(=O)N2CCN(C)CC2)cc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.41
KDM4E B2RXH2 3/20 0.39
TSHR P16473 2/20 0.39
PKM P14618 2/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
USP2 O75604 1/20 0.37
MAPT P10636 4/20 0.37
LMNA P02545 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPK1 P28482 2/20 0.37
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
MITF O75030 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843291 0.93 CA12 (0.37) HTTKDM4ETSHRPKMCYP2C19
SCHEMBL7699608 0.87 MEN1 (0.40) HTTKDM4ETSHRPKMCYP2C19
SCHEMBL16490263 0.82 MEN1 (0.39) HTTTSHRPKMCYP2C19SMN1; SMN2
SCHEMBL3844704 0.79 CNR2 (0.38) HTTTSHRCYP2C19SMN1; SMN2USP2
SCHEMBL3839806 0.78 KMT2A (0.37) HTTKDM4ETSHRCYP2C19SMN1; SMN2
SCHEMBL6403066 0.77 MEN1 (0.35) HTTKDM4ETSHRPKMCYP2C19
SCHEMBL17264739 0.76 MEN1 (0.33) HTTTSHRCYP2C19SMN1; SMN2USP2
SCHEMBL3839170 0.76 MEN1 (0.36) HTTKDM4ETSHRPKMCYP2C19
SCHEMBL19293385 0.74 KMT2A (0.38) HTTKDM4ETSHRCYP2C19SMN1; SMN2
SCHEMBL17626410 0.71 MEN1 (0.34) HTTTSHRCYP2C19SMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1702611-B1 Composition for dyeing keratinuous fibres comprising a direct sulfonamidoxanthenyl dye and dyeing process OREAL (FR) 2009-11-11 EP claimed
US-7367994-B2 Composition for dyeing keratin fibers, comprising a sulfonamidoxanthene direct dye, and dyeing process using the same L'ORéAL S.A. (FR) 2008-05-06 US claimed
EP-1702611-A2 Composition for dyeing keratinuous fibres comprising a direct sulfonamidoxanthenyl dye and dyeing process L'OREAL (FR) 2006-09-20 EP claimed
EP-1702611-B1 Composition for dyeing keratinuous fibres comprising a direct sulfonamidoxanthenyl dye and dyeing process OREAL (FR) 2009-11-11 EP disclosed
US-7367994-B2 Composition for dyeing keratin fibers, comprising a sulfonamidoxanthene direct dye, and dyeing process using the same L'ORéAL S.A. (FR) 2008-05-06 US disclosed
US-20060230545-A1 Composition for dyeing keratin fibers, comprising a sulfonamidoxanthene direct dye, and dyeing process using the same L'OREAL S.A. (FR) 2006-10-19 US disclosed
EP-1702611-A2 Composition for dyeing keratinuous fibres comprising a direct sulfonamidoxanthenyl dye and dyeing process L'OREAL (FR) 2006-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060230545-A1 Composition for dyeing keratin fibers, comprising a sulfonamidoxanthene direct dye, and dyeing process using the same KRT18, S100A4, DSG1 HTT 943/4885KDM4E 1302/4885TSHR 4528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.