Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405413 | 0.88 | GAA (0.59) | TSHRKDM4EGAAMAPTHSP90AA1 | |
| SCHEMBL6409638 | 0.75 | ALDH1A1 (0.63) | TSHRKDM4EGAAMAPTHSP90AA1 | |
| SCHEMBL10480359 | 0.75 | ALDH1A1 (0.51) | TSHRKDM4EGAAMAPTNPSR1 | |
| SCHEMBL10012854 | 0.75 | SMN1; SMN2 (0.52) | TSHRKDM4EMAPTHTTNPSR1 | |
| SCHEMBL5012601 | 0.73 | SMN1; SMN2 (0.41) | TSHRKDM4EHTTNPSR1ALDH1A1 | |
| SCHEMBL15801095 | 0.73 | KDM4E (0.45) | TSHRKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL4207462 | 0.73 | HSP90AA1 (1.00) | TSHRKDM4EGAAMAPTHSP90AA1 | |
| SCHEMBL1104402 | 0.73 | ALDH1A1 (0.55) | TSHRKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL587762 | 0.72 | HTT (0.64) | KDM4EGAAMAPTHTTNPSR1 | |
| SCHEMBL10480370 | 0.71 | CYP19A1 (0.45) | TSHRKDM4EMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TSHR 3470/4885KDM4E 3676/4885GAA 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.