⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988007 | 0.84 | SMN1; SMN2 (0.52) | — | |
| Iodide SCHEMBL4414352 | 0.82 | SMN1; SMN2 (0.50) | — | |
| Hydrochloric Acid SCHEMBL4417695 | 0.82 | SMN1; SMN2 (0.50) | — | |
| Bromide SCHEMBL4416367 | 0.82 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL2401566 | 0.81 | — | — | |
| SCHEMBL15136817 | 0.79 | SMN1; SMN2 (0.63) | — | |
| SCHEMBL34729 | 0.77 | — | — | |
| Water SCHEMBL17764770 | 0.77 | SMN1; SMN2 (0.61) | — | |
| SCHEMBL14499200 | 0.75 | — | — | |
| SCHEMBL9927858 | 0.75 | SMN1; SMN2 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |