Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 6/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.49 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17214740 | 0.87 | PRKAG1 (0.43) | PRKAG1PRKAB1PRKAA2STK17BRAB9A | |
| SCHEMBL19425608 | 0.85 | TYMP (0.57) | PRKAG1PRKAB1PRKAA2STK17BRAB9A | |
| SCHEMBL14907852 | 0.82 | GRK6 (0.59) | PRKAG1PRKAB1PRKAA2RAB9AHSD17B10 | |
| SCHEMBL17213026 | 0.81 | GRK6 (0.46) | RAB9AHSD17B10TYMPGRK6KDM4E | |
| SCHEMBL14907762 | 0.81 | GRK6 (0.60) | PRKAG1PRKAB1PRKAA2STK17BRAB9A | |
| SCHEMBL6410210 | 0.81 | HRH1 (0.43) | PRKAG1PRKAB1PRKAA2HRH1TYMP | |
| SCHEMBL14907754 | 0.80 | GRK6 (0.56) | PRKAG1PRKAB1PRKAA2RAB9ATYMP | |
| SCHEMBL14907849 | 0.80 | GRK6 (0.57) | PRKAG1PRKAB1PRKAA2RAB9AHSD17B10 | |
| SCHEMBL18552362 | 0.79 | GRK6 (0.46) | PRKAG1PRKAB1HSD17B10PRKAA1TYMP | |
| SCHEMBL16171164 | 0.79 | GRK6 (0.46) | PRKAG1PRKAB1HSD17B10PRKAA1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PRKAG1 772/4885PRKAB1 993/4885PRKAA2 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.