Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837990 | 0.95 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL5837472 | 0.93 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL5839158 | 0.91 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL5837063 | 0.90 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL5838656 | 0.89 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL5838734 | 0.88 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL5837134 | 0.87 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL6404461 | 0.86 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL5837885 | 0.86 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL5838960 | 0.82 | P2RX7 (0.65) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581507-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | Pfizer Products Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004058731-A1 | BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2004-07-15 | — | — | WO | disclosed |