Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13401419 | 0.83 | POLB (0.77) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL6410729 | 0.80 | ALDH1A1 (0.81) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL13856275 | 0.79 | POLB (0.71) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL5328274 | 0.78 | TP53 (0.75) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL5328282 | 0.78 | TP53 (0.75) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL13831407 | 0.77 | POLB (0.68) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL5331550 | 0.77 | ALDH1A1 (1.00) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL2421913 | 0.77 | RECQL (0.71) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL13856878 | 0.77 | NPSR1 (0.74) | TSHRALOX15NPSR1MEN1KMT2A | |
| SCHEMBL5327292 | 0.76 | POLB (0.67) | TSHRALOX15NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TSHR 3470/4885ALOX15 2151/4885NPSR1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.